Clinical Profile and Cognitive Status in Chronic Obstructive Pulmonary Disease's Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Universidad de Granada
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Cognitive impairment
- Last Updated
- 11 years ago
Overview
Brief Summary
Chronic obstructive pulmonary disease (COPD) is a chronic condition involving an impairment in functionality and in the execution of activities of daily life. The hypothesis of this study is to examine the relationship between cognitive status and clinical profile (respiratory, sleep quality, nutritional status) in patients with chronic obstructive pulmonary disease in two different moments: exacerbation or stable situation.
Detailed Description
Chronic obstructive pulmonary disease is a pathology with a systemic impact with a progressive evolution that is characterized by the presence of chronic airflow obstruction. Patients with COPD may have problems with cognitive functioning, either globally or in single cognitive domains, such as information processing, attention and concentration, memory, executive functioning and self-regulation. Several studies have determined the prevalence of cognitive impairment in COPD compared to healthy control subjects, reaching very high levels, 36% of COPD patients with mild cognitive impairment compared with 12 % non- COPD subjects.
Investigators
Marie Carmen Valenza
Assisstant professor
Universidad de Granada
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of chronic obstructive pulmonary disease with exacerbation or stable.
- •Signed written consent.
- •Medical approval for inclusion
Exclusion Criteria
- •Heart disease.
- •Neurological patients.
- •Severe cognitive impairment in order not to complete the assessment.
Outcomes
Primary Outcomes
Cognitive impairment
Time Frame: Baseline
The cognitive impairment will be measured using the Montreal Cognitive Assessment. The Montreal Cognitive Assessment is a test designed as a rapid screening instrument for mild cognitive dysfunction. It assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuoconstructional skills, conceptual thinking, calculations, and orientation.
Secondary Outcomes
- Sleep quality(Baseline)
- Activity monitoring(Baseline)
- Nutritional state(Baseline)
- Quality of life(Baseline)
- Cough(Baseline)
- Comorbidities(Baseline)
- Anxiety and depression(Baseline)
- Cognitive flexibility(Baseline)
- Forced vital capacity(Baseline)
- Forced expiratory volume in the first second(Baseline)