NCT00815594Unknown4 期
Bleb Vascularity Change After Subconjunctival Injection of Bevacizumab
Capital Medical University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2008年12月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- bleb vascular change
研究概览
简要总结
The occurrence of conjunctival scarring finally leads to the obstruction of the fistula tract created by the filtering surgery. Vascular endothelial growth factor is thought to be a key role in the formation of conjunctival scar, which play a pivotal role in the wound-healing process. So it seems that the recombinant human anti-VEGF antibody could inhibit angiogenesis, and reduce the conjunctival vascular formation in the wound-healing process after glaucoma filtering surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Glaucoma patients after trabeculectomy whose bleb is hyperaemia
排除标准
- •Affected eye has normal IOP
- •Not allergic with Avastin
结局指标
主要结局
bleb vascular change
时间窗: one day, one week, one month
次要结局
未报告次要终点
研究者
研究点 (1)
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