NCT00139945已完成不适用
Effects of Acute Ghrelin Infusion to Growth Hormone Deficient Adults: Growth Hormone and Cortisol Interaction
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Endogenous serum ghrelin levels
研究概览
简要总结
In growth hormone deficient patients: Determination of endogenous circulating ghrelin levels, ghrelin effects on insulin sensitivity, appetite, energy metabolism, and signal transduction in fat and muscle.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 60 yrs.
- •Verified hypopituitarism
- •Unchanged substitution treatment through 3+ months
- •Unchanged additional medical treatment
- •Oral and written informed consent
排除标准
- •Age below 18 or above 60 yrs.
- •Diabetes mellitus
- •body mass index > 30
- •Fasting hypoglycemia
- •Convulsions
- •Allergy to trial products
结局指标
主要结局
Endogenous serum ghrelin levels
时间窗: Same day as intervention
次要结局
- Insulin sensitivity, appetite, metabolism, intracellular signal transduction(Same day as intervention)
研究者
研究点 (2)
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