Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients
Not Applicable
Completed
- Conditions
- Hypopituitarism
- Registration Number
- NCT00139945
- Lead Sponsor
- University of Aarhus
- Brief Summary
In growth hormone deficient patients: Determination of endogenous circulating ghrelin levels, ghrelin effects on insulin sensitivity, appetite, energy metabolism, and signal transduction in fat and muscle.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
- Age between 18 and 60 yrs.
- Verified hypopituitarism
- Unchanged substitution treatment through 3+ months
- Unchanged additional medical treatment
- Oral and written informed consent
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Exclusion Criteria
- Age below 18 or above 60 yrs.
- Diabetes mellitus
- body mass index > 30
- Fasting hypoglycemia
- Convulsions
- Allergy to trial products
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Endogenous serum ghrelin levels Same day as intervention
- Secondary Outcome Measures
Name Time Method Insulin sensitivity, appetite, metabolism, intracellular signal transduction Same day as intervention
Trial Locations
- Locations (1)
Aarhus University Hospital
🇩🇰Aarhus, Denmark