NL-OMON44245
Completed
Not Applicable
Influence of exogenous growth hormone administration on circulating levels of Klotho in paediatric patients with isolated growth hormone deficiency. - KLOGIC
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Klotho levels in isolated growth hormone deficiency
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Subjects with newly diagnosed GHD according to the guideline \*Guideline for GH treatment in children\* with an indication for treatment with rhGH .
- •\- Boys \< 9 years old and girls \< 8 years old (pre\-pubertal).
- •\- No history of rhGH treatment in the last 6 months.
- •\- Providing informed consent by the parents.
Exclusion Criteria
- •\- Subjects with a combined pituitary hormone deficiency.
- •\- Patients taking medications or having concomitant illnesses likely to confound endpoint assessments (e.g.use of corticosteroids, androgens or anabole steroids, insulin).
- •\- Patients with hypothyroidism not adequately supplied with thyroid hormone.
- •\- Patients taking other experimental (i.e., non marketed) therapies.
- •\- Patients with any kind of kidney disease.
- •\- Patients with a single kidney.
Outcomes
Primary Outcomes
Not specified
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