SAFETY AND EFFICACY OF LOSARTAN ON DIALYSIS DEPENDANT CHRONIC KIDNEY DISEASE PATIENTS- AN INDIAN RANDOMISED CONTROLLED TRIA
Phase 4
- Conditions
- Health Condition 1: N11- Chronic tubulo-interstitial nephritis
- Registration Number
- CTRI/2019/01/017342
- Lead Sponsor
- INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patient of age within 18-60 year.
2.CKD stage 5 on haemodialysis.
3.On maintenance haemodialysis 3 per week.
4.A-V Fistula is used as haemodialysis access.
5.Haemoglobin level > 10gm%.
6.Echo-cardiographic evidence of Left ventricular hypertrophy.
7.Pre dialysis BP > 140/90 on 2 occassions.
8.No contraindication to any of the medication used in the study.
Exclusion Criteria
1.Life expectancy less than 6 months.
2.Pregnancy and unwilling to take contraception.
3.Patients with active infection.
4.Past history of allergy or side effects to losartan.
5.Contraindication to start losartan.
6.Unwilling to give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method