Evaluating the efficacy of Losartan ointment in wound healing

Phase 3

• Conditions: wound healing and preventing hypertrophic scars and keloids formation.; Hypertrophic scar; L91.0

• Registration Number: IRCT20201205049601N1
• Lead Sponsor: Artesh University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

The patient’s scar length should be more than 10 centimeter, or they should have several scars with total length of 10 centimeter.
The patient’s age should be between 18 to 50 years old.

Exclusion Criteria

The patients who did not regularly consume ointments will be excluded.
The patients who are pregnant, consume antihypertensive drugs, or have history of cancer, allergy and bleeding or discharge at scar site will be excluded.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scare assessment, Vancouver Scar Scale (VSS) assesses 4 variables: vascularity, height/thickness, pliability, and pigmentation. The overall score is between 0 to 13. Timepoint: Three and six months after ointment administration. Method of measurement: The evaluators are doctors who will use VSS or Vancouver scar scale to rate the scar change. Vancouver Scar Scale (VSS) assesses 4 variables: vascularity, height/thickness, pliability, and pigmentation. The overall score is between 0 to 13.

Secondary Outcome Measures

Name	Time	Method
Itching is an irritating sensation of the skin which will be measured by the Visual Analogue Scale. Timepoint: Three and six months after ointment administration. Method of measurement: The evaluators are doctors and will be measured by the Visual Analogue Scale.