Effect of topical Latanoprost combined with microneedling in the treatment of alopecia areata

Phase 3

Recruiting

• Conditions: alopecia areata.; other alopecia areata; L63.8

• Registration Number: IRCT20220316054304N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

age> 18 years old
AA coverage <25% of scalp surface
presence of 2-5 patches
discontinue of intralesional triamcinolone treatment at least 2 weeks earlier
stable disease without the appearance of a new patch or increase in the size of the patches for at least 15 days

Exclusion Criteria

allergy or hypersensitivity to any component of treatment products
pregnancy or lactation
any skin infection on treatment area
severe medical illness
simultaneous use of immunosuppressant or anticoagulant medication
progressive disease
posetive hair pull test

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Terminal hair growth change. Timepoint: The patients will be assessed in 2 every 2 weeks visits for procedures, and 3 months after the first visit. Method of measurement: ?Terminal hair growth change garde into following 6 grade:Grade 0:no change or further hair loss /Grade 1: regrowth of 1-24% terminal hair /Grade 2: regrowth of 25-49% terminal hair /Grade 3: regrowth of 50-74% terminal hair /Grade 4: regrowth of 75-99% terminal hair /Grade 5:regrowth of 100% terminal hair.

Secondary Outcome Measures

Name	Time	Method
Rate of patch size change. Timepoint: ?The patients will be assessed in 2 every 2 weeks visits for procedures, and 3 months after the first visit. Method of measurement: Rate of size change (%)= Baseline size-Follow up size/Baseline size ×???.;Patient satisfaction. Timepoint: ?The patients will be assessed in 2 every 2 weeks visits for procedures, and 3 months after the first visit. Method of measurement: A 5-point scale. 4: Extremely satisfied, 3:Very satisfied, 2: satisfied, 1: Slightly satisfied, 0: Not satisfied.