The Effect of Neuromuscular Electrical Stimulation

Not Applicable

Completed

• Conditions: Postoperative Coronary Artery Bypass Grafting (CABG); Chronic Obstructive Pulmonary Disease (COPD); Ventilatory Failure

• Registration Number: NCT00442728
• Lead Sponsor: Provinciale Hogeschool Limburg

Brief Summary

The effect of neuromuscular electrical stimulation on muscle atrophy in sedated patients on intensive care was studied. The aim of this study was to explore if electrical stimulation could prevent muscle atrophy.

Detailed Description

Patients were included in the study one day after administration when prolonged sedation and ventilation were expected. They were divided into intervention (n=7) and control (n=14) groups. For the intervention group, an intermittent neuromuscular electrical stimulation was applied daily for 30 minutes on the right thigh whereas the left thigh was used as a control. Heart rate, respiration rate, systolic and diastolic blood pressure and oxygen saturation were monitored before, during and after the electrostimulation. Perimeter of the right and left thighs was measured in both groups every 3 days at 5 cm above the upper edge of the kneecap.

Study Timeline

• Study Start: 2003-01
• Study Completion: 2003-06
• Study First Submitted: 2007-02-11
• Status Verified: 2007-03
• Study First Submitted QC: 2007-03-01
• Last Update Submitted: 2007-03-01
• Study First Posted: 2007-03-02
• Last Update Posted: 2007-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• . Prior to inclusion in the study, an informed consent was given by the family of the patients which was approved by the local Ethics Committee of the Virga Jesse Hospital and was performed in accordance with the standards of the 1964 Declaration of Helsinki.

Exclusion Criteria

• Patients were excluded from the study if they were still able to move their limb actively in spite of the sedation. Patients were also excluded if they had signs of recent ischemia or infarction for less then seven days. Patients with severe orthopaedic or vascular damage, i.e., fractures or oedema in the lower limbs were also excluded. Patients with an augmented risk for neuro electrical stimulation such as open wounds, hemodialysis or an arterial catheter at the stimulation area were also excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Perimeter of the right and left thighs was measured in both groups every 3 days at 5 cm above the upp

Trial Locations

Locations (1)

REVAL; 🇧🇪 Hasselt, Limburg, Belgium