An observational analysis of prevalence of adverse drug reaction in a tertiary care multispecialty hospital.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Occurrence of adverse drug reaction at each phase of medication cycle.
研究概览
简要总结
World Health Organization (WHO) defines an adverse drug reaction (ADR) as “one which is noxious and unintended, and which occurs in doses normally used in human for prophylaxis, diagnosis or therapy of disease, or for the modification of physiological functions.†According to the Centre for Health Policy Research, more than 50 percent of the approved drugs in the United States were associated with some type of adverse effect not detected prior to approval. At least one ADR has been reported to occur in 10 to 20% of hospitalized patients. Pharmacovigilance or ADR monitoring, launched by WHO in the 1960s in the wake of ‘thalidomide’ disaster, is currently an integrated global effort of more than 70 countries worldwide. After the “thalidomide tragedy†many countries have established drug monitoring systems for early detection and prevention of possible drug-related morbidity and mortality. The use of traditional and complementary drugs (e.g. herbal remedies) may also pose specific toxicological problems, when used alone or in combination with other drugs
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient hospitalized at IIH for treatment under: Surgical ward Oncology ward Executive ward FICU Private ward Medical ward.
排除标准
- •Patient below 18 HIV Patient and leprosy LAMA cases Medico legal cases.
结局指标
主要结局
Occurrence of adverse drug reaction at each phase of medication cycle.
时间窗: At discharge.
次要结局
- Awareness of Adverse drug reaction in each phase of medication use cycle.(Post discharge.)
研究者
Palak Arya
Indus International Hospital