Clinical research of Xinglou Chengqi Decoction on improving post-stroke cognitive impairment due to phlegm heat and viscera excess syndrome based on brain-gut interactio
- Conditions
- Post-stroke Cognitive Impairment
- Registration Number
- ITMCTR2100004688
- Lead Sponsor
- Wenzhou Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. The patients met the diagnostic criteria of ischemic stroke in Western medicine.
2. The patients met the diagnostic criteria of vascular cognitive impairment and MMSE score was less than 25.
3. Conformity with the diagnosis of TCM stroke disease name.
4. Within 2 weeks to 6 months from the date of the onset of the disease, the patient has clear consciousness, sufficient visual and auditory abilities, and can cooperate with neuropsychological assessment.
5. Aged 18-85 years (gender without special requirements).
6. Voluntary subjects who sign the informed consent.
1. Lacunar infarction,transient ischemic attack.
2. Stroke patients confirmed by examination to be caused by brain tumors, brain trauma, hematological diseases, etc.
3. Patients with cerebral embolism caused by rheumatic heart disease,coronary heart disease and other cardiac diseases combined with atrial fibrillation.
4. Patients with serious primary diseases such as cardiovascular,liver,kidney,hematopoietic and immune systems,or patients with tumors,psychiatric patients,and those without self-knowledge ability.
5. Pregnant and lactating women,allergic constitution.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum brain-gut peptide;
- Secondary Outcome Measures
Name Time Method constipation assessment;Mini Mental State Examination Scale (MMSE);