ISRCTN25867281未知未知
Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets
European Commission, Research Directorate-General (Belgium)0 个研究点目标入组 755 人开始时间: 2006年5月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 发起方
- 入组人数
- 755
研究概览
简要总结
2006 Results article in http://www.ncbi.nlm.nih.gov/pubmed/16871334 results 2012 Results article in http://www.ncbi.nlm.nih.gov/pubmed/22952648 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Body mass index (BMI) =30
- •2. White European (by self report)
- •3. Age 20-50 years
- •4. Pre-menopausal (women)
排除标准
- •1. Drug-treated hypertension
- •2. Drug-treated diabetes
- •3. Drug-treated hyperlipidaemia
- •4. Drug-treated thyroid disease
- •5. Use of anorexigenic agents
- •6. Anti-epileptic drugs
- •7. Anti-Parkinsonian drugs
- •8. Use of barbituates, benzodiasapines, beta-blockers, butyrophenones, carbonic anhydrase inhibitors, diuretics, dopamine reuptake inhibitors, digoxin, fibrates, fish oil supplement, glucocorticoids, immunosuppressives, insulin , laxatives, monoamine oxidase (MAO) inhibitors, niacin (>150 mg per day), nicotine, oral hypoglycemics, orlistat, phenothiazines, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, statins, thyroid hormone, triamterene, tricyclic antidepressants, warfarin or zonisamide
- •9. Surgically-treated obesity
- •10. Participation in ongoing drug trials
- •11. Pregnant women
- •12. Alcohol or drug abuse
- •13. Weight change of >3 kg within 3 months prior to clinical investigation day
研究者
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