Transcranial magnetic stimulation during fMRI; investigating neuronal activation during TMS
Completed
- Conditions
- geen, onderzoek in gezonde proefpersonenn.v.t.
- Registration Number
- NL-OMON46090
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Healthy participants aged 18 years or older
Exclusion Criteria
- Ferrous objects in or around the body that can not be removed
- Drug or alcohol abuse over a period of six months prior to the experiment
- History of closed- or open-head injury
- History of neurological illness or endocrinological dysfunction
- History of psychiatric disease
- History of epilepsy
- Occurrence of epilepsy in 1st degree family
- Major medical history
- Chronic use of medication
- For women: pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are the TMS induced percent signal change in BOLD MR<br /><br>images over the whole brain, and the spatial correspondence between activated<br /><br>brain areas measured by BOLD and predicted by TMS field modelling. </p><br>
- Secondary Outcome Measures
Name Time Method <p>A secondary endpoint is the ECG/EMG output from thumb movement during TMS<br /><br>application.</p><br>