MR-informed, navigated transcranial magnetic stimulation with interleaved functional MR-imaging
Recruiting
- Conditions
- depressive symptoms with bipolar disorder, negative symptoms with schizophrenia-like disordersDepressive episodeF32
- Registration Number
- DRKS00031319
- Lead Sponsor
- Klinik für Psychiatrie und Psychotherapie, LMU Klinikum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
planned NTBS treatment (patients)
- ability to give informed consent
Exclusion Criteria
- Individuals at suicidal risk
- Individuals diagnosed with a significant neurological disorder or insult, individuals with a history of traumatic brain injury and in general, individuals with any history of seizures
- Any relevant instable medical condition (e.g. acute, unstable cardiac disease)
- Individuals with non-removable, ferromagnetic implants/material in head and/or body parts that cannot be safely removed
- in general individuals with contraindications for MRI or TMS
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Direct changes of brain activity to TMS intervention, measured via BOLD signal changes in functional MRI before, during, and after TMS intervention
- Secondary Outcome Measures
Name Time Method Correlations of brain activity changes with further characteristics of participants (such as MR-derived information, questionnaires etc.) as well as at the stage of NTBS treatment (beginning, end of treatment, follow-up...)