Predictive value of nailfold Capillaroscopy and Antinuclear antibodies in children with RaYnaud’s phenomeno
- Conditions
- Raynaud's phenomenon
- Registration Number
- NL-OMON28940
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Diagnoses of Raynaud's phenomenon
- Underwent NCM when they were under 18 years of age
Exclusion Criteria
None
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of the study is to determine the sensitivity and specificity of NCM in combination with ANA for predicting an underlying CTD in children with Raynaud's.
- Secondary Outcome Measures
Name Time Method - To study the changes of the nailfold capillaroscopic pattern over time (>5 years): pattern, number of capillaries, number of giant capillaries, hemorrhages<br /><br>- To describe the characteristics of our cohort of children/young adults with Raynaud’s phenomenon with a follow-up of >5 years<br /><br>- To study the predictive value of symptoms specific for CTD and abnormal lab tests (CRP, BSE, kidney function, complement C3 and C4, erythrocyteuria, cryoglobulinemia)