Evaluation of capillary pathologies by nailfold capillaroscopy in patients with psoriasis vulgaris

Recruiting

• Conditions: L40.0; M07.00; Psoriasis vulgaris

• Registration Number: DRKS00012856
• Lead Sponsor: niversitäts-Hautklinik Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Moderate to severe psoriasis vulgaris and/or Psoriasis arthritis for at least 6 months. Signed written informed consent.

Exclusion Criteria

Patients under current exposure to any anti-psoriatic systemic therapy. Active ongoing inflammatory diseases. Patients that are unable to give informed consent.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective of this study is to investigate nailfold capillary patterns in 50 patients with psoriasis vulgaris alone or accompanying psoriasis arthritis compared to 25 healthy subjects. The changes will be evaluated only one time by means of nailfold capillaroscopy at the baseline visit.

Secondary Outcome Measures

Name	Time	Method
A secondary objective of this study is to analyze the impact of the psoriasis area and severity score (PASI), nail psoriasis and demographic and clinical data e.g. age, gender, duration of the disease, manifest cardiovascular disease on nailfold capillaroscopy patterns. Date will be retrieved during the baseline visit.