Skin changes in patients of Diabetes Mellitus and prediction of long term diabetes induced complications in kidney and eye through examination of vessels over nail fold.
- Conditions
- Health Condition 1: null- Diabetes Mellitus cases with cutaneous manifestations
- Registration Number
- CTRI/2018/03/012719
- Lead Sponsor
- Ruchi Shah
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
•All type-II Diabetes Mellitus cases patients attending the Diabetic clinic conducted in O.P.D. 18 ,every Wednesday and daily Medicine (O.P.D.18) and Skin and V.D. O.P.D. having one or more of the following cutaneous manifestations:
Vascular Damage:
-Leg ulceration
-Wet gangrene of the foot
-Erysipelas like erythema
-Diabetic dermopathy
-Rubeosis
Neurological Damage:
-Diabetic foot
-Diabetic foot ulcer
Infections
Obesity and hyperlipidemia related skin disease:
-Acanthosis nigricans
-Skin tags
-Eruptive Xanthomas of the skin
Treatment related Skin manifestations:
-Insulin lipodystrophy
-Allergic reactions to Insulin
-Allergic reactions to oral hypoglycemic drugs
Disease associations and genetic syndromes:
-Reactive perforating collagenosis(Folliculitis)
-Autoimmune disease
-Genetic and other systemic disease
Miscellaneous:
-Granulomatous disorders(Necrobiosis Lipoidica)
-Stiff skin and joints:
Cheiroarthropathy
Finger pebbles
Sceleredema diabeticorum
-Pruritus
-Diabetic Bullae
•Other dermatologic diseases having relation with Metabolic syndrome like Psoriasis
•Cases having Autoimmune diseases like Systemic Lupus Erythematosus, cleroderma, Systemic Sclerosis which can give rise to abnormal capillaroscopic findings.
•Smoking
•Cases with known liver disease or other multi-system disorders
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢To study the cutaneous manifestations of Diabetes mellitus <br/ ><br>â?¢To demonstrate nailfold capillaroscopy changes due to diabetic microangiopathy <br/ ><br>â?¢To study the correlation between cutaneous and systemic manifestations of Diabetic microangiopathy in terms of Retinopathy and nephropathy <br/ ><br>Timepoint: patients will be assessed at the time of enrollment in the study only.
- Secondary Outcome Measures
Name Time Method To study the correlation between cutaneous and systemic manifestations of Diabetic microangiopathy in terms of Retinopathy and nephropathyTimepoint: patients can be followed up every 6 months for new manifestations and ophthalmic checkup