Association of different phenotypes of neutrophil granulocytes and proinflammatory cytokines with the pathogenesis and the progression of periodontitis
- Conditions
- K08.9Disorder of teeth and supporting structures, unspecified
- Registration Number
- DRKS00034061
- Lead Sponsor
- Poliklinik für Zahnerhaltung und Parodontologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
Inclusion criteria for one patient
- Age: = 18 years
- ASA status 1 and 2
- Non-smoker
- Consent of the patient
Exclusion Criteria
Exclusion criteria for a patient
- Children (underage patients)
- Poor general condition (ASA status =3)
- No consent from the patient
- Less than 20 teeth
- Stage I, II, IV periodontitis
- Pregnancy
- Diabetes mellitus
- Rheumatoid arthritis
- Diseases with immunosuppression
- Patients with an increased risk of infective endocarditis
- Patients with increased risk of drug-induced osteonecrosis of the jaw
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tooth loss enquiry 60 months after the start of the study
- Secondary Outcome Measures
Name Time Method Periodontal status after 6, 12, 24, 36 and 48 months