The effect of folate supplementation on serum hepatic enzymes, lipid profile and homocystein levels in patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled trial

Ilam University of Medical Sciences0 个研究点目标入组 40 人开始时间: 待定最近更新: 2018年2月22日

适应症

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•Inclusion Criteria: Diagnosis to have non alcoholic fatty liver disease confirmed with ultrasonography result; ages above 18 ; serum alanine transaminase enzyme level higher than 30 U/L ; Diabetic patients will include if they have been recently diagnosed with diabetes and not using blood glucose lowering drugs or if they consume insulin and metformin, it would pass at least 6 months from starting the treatment and during this period the dose of metformin and insulin are not changed. Exclusion criteria: Alcohol consumption greater than 20 g per day; diseases such as hereditary hemochromatosis; Wilson's disease; an enzyme deficiency a1 Antitripsin; history of jejunoileal bypass surgery or gastroplasty; experience to perform the total parenteral nutrition at 6 months before; consomption of statins and hepatotoxic drugs such as calcium channel blocker; methotrexate; amiodarone; chloroquine; a history of hypothyroidism and Cushing's syndrome; Intake of folate; B12; vitamin E; omega-3 supplements during last 6 months.

发起方

Ilam University of Medical Sciences