Constraint Induced Aphasia Therapy in Stroke Patients in Acute Stage.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 主要终点
- Change of aphasia by Aachener Aphasia Test (AAT)
研究概览
简要总结
Constraint-induced aphasia therapy (CIAT) has proven effective in stroke patients. It has remained unclear, however, whether intensity of therapy or constraint is the relevant factor. This study will give an answer to this question to improve speech and language therapy.
详细描述
Although there is clear evidence that aphasia therapy is effective, questions remain as to the intensity of administered therapy, the preferred therapeutic approach and its initiation with regard to stroke onset. CIAT is a a high intense group therapy administered over 2 weeks. Additionally, patients have to communicate solely in spoken words or sentences (constraint). This study compares CIAT with an approach of the same intensity without constraints and a less intense house-typical therapeutic approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 39 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •first ever stroke
- •suffering from aphasia
排除标准
- •severe cognitive or attentional impairments
- •severe depression
- •left-handedness
- •severe dysarthria
- •apraxia of speech
- •severe deafness
- •additional neurological diseases affecting speech (e.g. Parkinson's disease)
结局指标
主要结局
Change of aphasia by Aachener Aphasia Test (AAT)
时间窗: pretreatment and within 24 h post intervention
次要结局
- Change of Communication Activity Log (CAL)(pretreatment and within 24 h post intervention)
研究者
Hartwig Woldag
Head of departement NRZ Leipzig
University of Leipzig