PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- To assess the prevalence of obstructive sleep apnea syndrome in patients who have experienced an amnestic stroke.
研究概览
简要总结
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at present. A recent study on a small sample size (N=29) highlighted an association between obstructive sleep apnea syndrome and amnesic stroke. Our study seeks to confirm or refute these results on a larger cohort (N=200-250). A better understanding of the pathophysiological processes involved would open up new therapeutic avenues.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients seen for consultation in the Neuropsychology Department of Strasbourg University Hospital between March 1, 2015 and December 31, 2021 following an episode of amnestic stroke meeting the Hodges and Warlow criteria:
- •The stroke must have been documented and reported by a competent witness present during the stroke.
- •Anterograde amnesia during the stroke.
- •Absence of vigilance, personality, and cognitive disorders other than memory disorders (aphasia, apraxia, etc.).
- •Absence of focal neurological symptoms during the episode and its aftermath.
- •Absence of epileptic manifestations.
- •Resolution of the episode in less than 24 hours.
- •Exclusion of patients with a history of recent head trauma or active epilepsy (undergoing regular treatment or having experienced a seizure in the last 2 years).
- •Subjects who have not expressed opposition to the reuse of their data for scientific research purposes.
排除标准
- •Patients who have expressed opposition to the retrospective reuse of their data for scientific research purposes.
- •Patients with active epilepsy
- •Patients with recent head trauma
- •Patients with an MMS < or equal to 25
- •Subject under guardianship or curatorship
- •Subject under judicial protection
结局指标
主要结局
To assess the prevalence of obstructive sleep apnea syndrome in patients who have experienced an amnestic stroke.
时间窗: Within the last 2 years
Presence or absence of obstructive sleep apnea syndrome reported by a witness present during the stroke.
次要结局
未报告次要终点