Postoperative anterograde amnesia by remimazolam and antagonism with flumazenil
Not Applicable
- Conditions
- Patients who will undergo general anesthesia for elective surgery of lower limbs
- Registration Number
- JPRN-UMIN000051924
- Lead Sponsor
- Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients contraindicate or with allergy to remimazolam or flumazenil (2) Patients contraindicate to neuraxial block (3) Patients with cognitive impairment (4) Patients with intracranial disease or cerebrovascular disease (5) Patients who take psychiatric medication (6) Patients who usually take benzodiazepine (7) ASAPS 3 or 4 (8) Patients decided not to be eligible for this study (9) Patients administrated flumazenil for clinical reason (not for research protocol)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of memory test by flumazenil
- Secondary Outcome Measures
Name Time Method Time course of the score in memory test, Incidence of retrograde amnesia/ postoperative delirium/ postoperative sleep disorder