Effect of Flumazenil on Postoperative Memory Retention Time after General Anesthesia with Remimazolam: A Randomized Controlled Trial

Not Applicable

Recruiting

Conditions: Patients scheduled for breast surgery under general anesthesia

Registration Number: JPRN-UMIN000052659

Lead Sponsor: Kyushu University Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 44

Inclusion Criteria

Not provided

Exclusion Criteria

Patients will be excluded from the study if any of the following apply 1) Patients with a history of hypersensitivity to remimazolam or flumazenil 2. patients with acute angle closure glaucoma, myasthenia gravis, epilepsy patients who have been receiving benzodiazepines for a long period of time, or have a history of serious complications or illnesses that would make them inappropriate for participation in this study Patients who are deemed inappropriate for inclusion in the study by the investigator. 4. (4) Patients with ASA physical status of IV or higher, shock, or coma (5) Patients with cognitive impairment 5. patients with cognitive impairment

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time for 80% of patients in each group to be able to memorize. If the patient had no memory of Illustration A 1 hour after leaving the operating room, one more poster (Illustration B) was shown, and 2 hours after leaving the operating room, the patient's memory of Illustration B was checked. If the patient has no memory of Illustration B, one more poster (Illustration C) is shown, and 3 hours after leaving the operating room, the patient's memory of Illustration C is checked. If the patient remembers Illustration C, the evaluation is terminated at that point.

Secondary Outcome Measures

Name	Time	Method
(1) Percentage of patients whose memory of the poster shown after awakening from anesthesia could be confirmed 1 hour after leaving the operating room. (2) Dosage and frequency of analgesic use from the time of return to the ward to 3 hours after surgery (3) Dosage and frequency of antiemetic use from the time of return to the ward to 3 hours after surgery