Effect of Flumazenil Drip On Speed Of Recovery And Prevention Of Complications In Severe Acute Benzodiazepine Toxicity

Phase 2

• Conditions: Poisoning by, adverse effect of and underdosing of hydantoin derivatives; T42.0; Benzodiazepine poisoning.

• Registration Number: IRCT20120629010133N3
• Lead Sponsor: IMAD (National Institute for Medical Research Development)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Severely benzodiazepine-poisoned patients (in need for intubation and mechanical ventilation) with otherwise normal vital signs

Exclusion Criteria

Abnormal vital signs on presentation,
history of seizure,
history of ingestion or use of any drug/medication that can predispose the patient to seizure,
history of head trauma,
possible brain edema and increased intracranial pressure,
history of hypoxemia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality-. Timepoint: 7 days after admission. Method of measurement: Observation and questionnaire recording.;Complications during hospitalization. Timepoint: 7 days after admission. Method of measurement: Observation and questionnaire recording.;Intubation. Timepoint: 7 days after admission. Method of measurement: Observation and questionnaire recording.

Secondary Outcome Measures

Name	Time	Method
Hospitalization period. Timepoint: At discharge or death. Method of measurement: Observation and questionnaire recording.