Mapping lymphatic drainage patterns in recurrent oral cavity squamous cell carcinoma using sentinel lymph node biopsy.
Not Applicable
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/05/067253
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Biopsy proven recurrent or second primary invasive squamous cell carcinoma of oral
cavity on the side which has previously been treated with neck dissection or
radiation
2 Clinicoradiologically T1, T2, T3 tumors with node negative disease and no distant
metastases on whole body PET CECT
3 Planned for curative intent surgical excision of the primary tumor with elective neck dissection of the contralateral side
Exclusion Criteria
1 Patients with reduced mouth opening where peritumoral injection of radiotracer along 4 quadrants not possible
2 Patients who are not suitable for curative intent surgery or neck dissection for medical or surgical reasons
3 Patients in whom bilateral neck dissection has been done in the previous surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To identify the patterns of lymphatic drainage patterns in patients <br/ ><br>with recurrent OSCC with previously treated neckTimepoint: 1 Month
- Secondary Outcome Measures
Name Time Method To assess the sensitivity, specificity, positive and negative predictive value of SLNBTimepoint: 1 Month;To study the accuracy of PET CECT and SLNB for detection of LN metastases in recurrent OSCC as compared to the final histopathology reportTimepoint: 1 Month