The Usefulness of the Combination of Preoperative Assessment of Optic Nerve Sheath Diameter and Heart Rate Variability to Predict Intraoperative Brain Condition in Patients With Supratentorial Tumors
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- DyAnsys, Inc.
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Brain relaxation
Study Overview
Brief Summary
This study aims to determine the relationship between heart rate variability and intraoperative brain relaxation conditions in patients with brain tumors.
Detailed Description
Patients undergoing brain surgery for treatment of brain tumors will be studied to determine the relationship between heart rate variability and intraoperative brain relaxation conditions.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient aged 18 to 75 years
- •ASA(American Society of Anesthesiologists ) I - III
- •Patients undergoing surgery for supratentorial tumors
- •Glasgow coma scale > 10
Exclusion Criteria
- •Patient aged below 18 and above 75 years.
- •Pregnancy
- •ASA(American Society of Anesthesiologists) IV-V
- •Previous cranial surgery
- •Morbid obesity ( BMI>40)
- •Ocular injury/ Glaucoma
- •Head injury
- •Patient on beta blockers, ACE(angiotensin-converting-enzyme) inhibitors, Clonidine
- •Diabetes mellitus for more than 5 years
Outcomes
Primary Outcomes
Brain relaxation
Time Frame: 2hours
1. Tight Brain-the brain surface is jutting out or expanding beyond the craniotomy margins, brain pulsations are not clearly defined. 2. Brain surface at level of craniotomy margins, Brain pulsations faintly observed 3. Brain surface just below the surface of craniotomy margin. Brain pulsations well seen. 4. Brain surface well below the surface of craniotomy margin, well retracted in to the cranial cavity with good brain pulsations.Brain relaxation score will me measured only once. There is no follow up
Secondary Outcomes
- Hemodynamic Measurement-Heartrate(2hours)
- Hemodynamic Measurement-Bloodpressure(2hours)