Preoperative Heart Rate Variability and Baroreflex Sensitivity in ASO Patients During Various Sleep Stages

Completed

• Conditions: Arteriosclerosis Obliterans

• Registration Number: NCT00712946
• Lead Sponsor: GE Healthcare

Brief Summary

The goal of this study is to evaluate the possible preoperative predictive value of altered heart rate variability (HRV) and baroreflex sensitivity in different sleep stages for postoperative adverse cardiac events (i.e. arrhythmia or myocardial ischemia needing hospitalization or medication, myocardial ischemia assessed by enzyme release, myocardial infarction, sudden cardiac death, stroke) in arteriosclerosis obliterans patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-03
• Study First Submitted: 2008-07-08
• Study First Submitted QC: 2008-07-08
• Study First Posted: 2008-07-10
• Status Verified: 2010-03
• Study Completion: 2010-12
• Last Update Submitted: 2011-04-27
• Last Update Posted: 2011-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 103

Inclusion Criteria

• Age > 40 years
• ASO
• Elective vascular surgery patient (i.e. infra-inguinal bypass procedure)

Exclusion Criteria

• Other than sinus rhythm
• Lack of co-operation
• Major surgery less than 3 months preoperatively
• Sleep apnoea
• Dialysis treatment
• CABG less than 3 years earlier

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Department of Anesthesiology and Intensive Care, Turku University Hospital; 🇫🇮 Turku, Finland