Transcranial Doppler Ultrasonography and Brain Death
Completed
- Conditions
- Brain Dead
- Interventions
- Other: Transcranial doppler
- Registration Number
- NCT01070563
- Lead Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
- Brief Summary
In France the diagnosis of brain death relies on electroencephalography (EEG) or cerebral angiography. Concerning the latter a time of 6 hours is mandatory between the clinical diagnosis and the realization of the cerebral computed tomography (CT) angiography. Transcranial doppler (TCD) is not recommended in the french guidelines for the diagnosis of brain death. In other countries, some flow patterns allow to confirm the diagnosis of brain death. The hypothesis of our study is that TCD could shorten the time between the clinical diagnosis of brain death and the realization of the CT angiography.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
- brain death patients
Exclusion Criteria
- craniectomy
- post anoxia encephalopathy
- no TCD performed before the clinical diagnosis of brain death
- transtemporal approach impossible
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description TCD Transcranial doppler When the diagnosis of brain death is made, TCD is performed and then every 2 hours until the flow patterns compatible with brain death are found. Then a CT angiography is performed.
- Primary Outcome Measures
Name Time Method Time between clinical diagnosis of brain death and realization of CT angiography the outcome is assessed when the CT angiography is performed
- Secondary Outcome Measures
Name Time Method Number of CT angiography required for the diagnosis of brain death the outcome is measured until the diagnosis of brain death is confirmed
Trial Locations
- Locations (1)
Centre Hospitalier Universitaire de Nice
🇫🇷Nice, France