Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy

Not Applicable

Completed

• Conditions: Nephrolithiasis; Analgesia; Anesthesia; Renal Stone
• Interventions: Procedure: Paravertebral Block; Procedure: Erector Spinae Plain Block

• Registration Number: NCT04998435
• Lead Sponsor: Nazmy Edward Seif

Brief Summary

Nowadays, Percutaneous Nephrolithotomy (PCNL) has been the surgical procedure of choice for renal stones larger than 2cm or staghorn stones. Yet, the associated postoperative pain is a major drawback. The regional anesthetic management of pain in PCNL operation has been of great concern. The introduction of ultrasound guided erector spinae plane block and paravertebral plane block has been under great focus regarding the efficacy of postoperative pain management. Paravertebral plane block (PVB) is a regional nerve block technique that depends on local anesthetic injection adjacent to the vertebra to block spinal nerve roots in a dermatomal distribution. Erector spinae plane block (ESPB) is a newer regional anesthesia technique that depends on injecting local anesthetic (LA) in a plane between the transverse process and erector spinae muscle. The LA diffuses into the paravertebral space and spreads on both rami (dorsal and ventral) of spinal nerves through spaces between adjoining vertebrae.

The aim of this study is to compare the effect of ultrasound guided Paravertebral blockade versus Erector spinae blockade on postoperative opioid use as well as postoperative pain control in patients undergoing unilateral PCNL.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-07-27
• Study First Submitted QC: 2021-08-02
• Study First Posted: 2021-08-10
• Study Start: 2021-08-11
• Primary Completion: 2022-01-01
• Study Completion: 2022-01-01
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-18
• Last Update Posted: 2022-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• ASA I - II.
• Patients undergoing unilateral percutaneous nephrolithotomy (PCNL) surgery under general anesthesia.

Exclusion Criteria

• Patient refusal.
• Uncooperative patients.
• Allergy to local anesthetics.
• Infection or anatomical abnormality at injection site.
• Coagulopathy.
• Bilateral PCNL.
• Spinal anesthesia or any other regional anesthesia.
• Block failure: the block will be considered a failed block if the patient requires more than two doses of rescue analgesia in the first hour postoperatively.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PV group	Paravertebral Block	Paravertebral Block
ESPB group	Erector Spinae Plain Block	Erector Spinae Plain Block

Primary Outcome Measures

Name	Time	Method
Morphine consumption.	24 hours	Total dose of Morphine (measured in mg) given intra-venously to the patient post-operatively.

Trial Locations

Locations (1)

Cairo University Hospitals; 🇪🇬 Cairo, Egypt