Ultrasound Guided Anterior Quadratus Lumborum Block

Not Applicable

Completed

• Conditions: Postoperative Pain; Ultrasound
• Interventions: Drug: Morphine Sulfate; Procedure: Group P; Procedure: Group A

• Registration Number: NCT03425162
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Percutaneous nephrolithotomy (PNL) is frequently used today for renal stones. percutaneous nephrolithotomy (PNL) procedure has become the treatment of choice for many patients with symptomatic renal stones . Patients undergoing PNL suffer from acute postoperative pain, despite a multimodal analgesic regime.

This is a randomised controlled trial efficacy of the anterior Quadratus Lumborum Block (QLB) in terms of analgesic efficacy in patients who undergo percutaneous nephrolithotomy.

Detailed Description

Many analgesic procedures such as NSAID, opioid and regional anesthesia procedures are used as a part of multimodal analgesia for postoperative Percutaneous nephrolithotomy pain.

In this study we will use the ultrasound -guided anterior Quadratus Lumborum Block . Local anesthesic will be injected between quadratus lumborum muscle and psoas muscle with ultrasound.Analgesic effect of this block will be detected by using morphine consumption and visual analogue scale .

Study Timeline

• Study First Submitted: 2018-02-01
• Study First Submitted QC: 2018-02-01
• Study First Posted: 2018-02-07
• Study Start: 2018-02-12
• Primary Completion: 2018-08-18
• Study Completion: 2018-08-18
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-20
• Last Update Posted: 2018-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent elective Percutaneous nephrolithotomy

Exclusion Criteria

• Previous history of opioid use preoperatively,

  • Allergy to local anesthetics,
  • The presence of any systemic infection,

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group P	Group P	Group P:PCA (morphine)
Group A	Group A	Group A:Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 bupivacaine+PCA (morphine)
Group A	Morphine Sulfate	Group A:Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 bupivacaine+PCA (morphine)
Group P	Morphine Sulfate	Group P:PCA (morphine)

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale	Postoperative 24 hours	Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0= no pain, 10=intolerable pain)

Secondary Outcome Measures

Name	Time	Method
morphine consumption	Postoperative 24 hours	morphine consumption
additional analgesic use	Postoperative 24 hours	additional analgesic use
side effect profile	Postoperative 24 hours	side effect profile (Nausea and vomiting scale,Hypotension,Ramsay Sedation Scale); 1. Nausea and vomiting scale (nausea-vomiting scale (NVS): 1. No nausea is present, 2. Mild nausea is present. 3. Severe nausea is present. 4. Vomiting is present) In case of a NVS score of \>3, an anti-emetic drug was administered.; 2. Hypotension; 3. Ramsay Sedation Scale (Ramsay Sedation Scale (RSS) : 1. Anxiety, agitation are present; 2. Cooperated, awake; 3. Sedatized, response to commands; 4. Sleepy, immediately awoken by auditory stimulus or glabella tap; 5. Sleepy, deep response to auditory stimulus or glabella tap and 6. Sleepy, no response to auditory stimulus or glabella tap )

Trial Locations

Locations (1)

University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital; 🇹🇷 Bursa, Turkey