CTRI/2020/07/026637尚未招募不适用
Attenuation of cardiovascular response to laryngoscopy and endotracheal intubation: comparative evaluation of IV magnesium sulfate (20mg/kg) Vs IV lignocaine (1.5mg/kg)
MEDICAL COLLEGE SUPPLY1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年2月8日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Attention of cardiovascular responses such as Heart rate and Blood pressure after Laryngoscopy and tracheal intubation.
研究概览
简要总结
Laryngoscopy and tracheal intubation violate the patients protective airway reflexes and lead to adverse hemodynamic and cardiovascular responses. several agents have been tried to obtund the pressor response. Recently, the role of magnesium has been evaluated for different purposes for anaesthetic and Intensive care units. We have undertaken this study to assess the efficacy of intravenous Magnesium sulphate as premedication in attenuating the pressor responses to laryngoscopy and tracheal intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •PATIENT REQUIRING GENERAL ANEAESTHESIA UNDER ASA GRADING I AND II.
排除标准
- •KNOWN HYPERTENSIVES POOR LEFT VENTRICULAR FUNCTION EMERGENCY SURGERY DIABETICS DIFFICULT AIRWAY IMPAIRED RENAL FUNCTION AND ELECTROLYTE IMBALANCE.
结局指标
主要结局
Attention of cardiovascular responses such as Heart rate and Blood pressure after Laryngoscopy and tracheal intubation.
时间窗: First five minutes after Laryngoscopy and tracheal intubation.
次要结局
- Hemodynamic stability at the start of the surgery.(Fifteen minutes after induction of general anaesthesia.)
研究者
研究点 (1)
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