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A clinical study to compare the effects of two drugs Lignocaine and Magnesium sulfate for cardiovascular response to Laryngoscopy and endotracheal intubation.

Not yet recruiting
Conditions
Medical and Surgical,
Registration Number
CTRI/2020/07/026637
Lead Sponsor
MEDICAL COLLEGE SUPPLY
Brief Summary

Laryngoscopy and tracheal intubation violate the patients protective airway reflexes and lead to adverse hemodynamic and cardiovascular responses. several agents have been tried to obtund the pressor response. Recently, the role of magnesium has been evaluated for different purposes for anaesthetic and Intensive care units. We have undertaken this study to assess the efficacy of intravenous Magnesium sulphate as premedication in attenuating the pressor responses to laryngoscopy and tracheal intubation.

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

PATIENT REQUIRING GENERAL ANEAESTHESIA UNDER ASA GRADING I AND II.

Exclusion Criteria

KNOWN HYPERTENSIVES POOR LEFT VENTRICULAR FUNCTION EMERGENCY SURGERY DIABETICS DIFFICULT AIRWAY IMPAIRED RENAL FUNCTION AND ELECTROLYTE IMBALANCE.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Attention of cardiovascular responses such as Heart rate and Blood pressure after Laryngoscopy and tracheal intubation.First five minutes after Laryngoscopy and tracheal intubation.
Secondary Outcome Measures
NameTimeMethod
Hemodynamic stability at the start of the surgery.Fifteen minutes after induction of general anaesthesia.

Trial Locations

Locations (1)

MAJOR OT, NEUROSURGERY OT, ORTHOPEDIC OT, UROSURGERY OT

🇮🇳

Ahmadabad, GUJARAT, India

MAJOR OT, NEUROSURGERY OT, ORTHOPEDIC OT, UROSURGERY OT
🇮🇳Ahmadabad, GUJARAT, India
SARAVANAN VK
Principal investigator
7708009226
saarvananvks1327@gmail.com

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