Effect of Cerebral and Cerebellar Repetitive Transcranial Magnetic Stimulation on Motor Function in Stroke Patients

Samsung Medical Center1 site in 1 country56 target enrollmentOctober 2, 2020

ConditionsStroke Repetitive Transcranial Magnetic Stimulation rTMS Motor Recovery

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stroke
Sponsor: Samsung Medical Center
Enrollment: 56
Locations: 1
Primary Endpoint: Difference of upper limb motor score in Fugl-Meyer assessment
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients. This study is to investigate whether the cerebral-cerebellar repetitive transcranial magnetic stimulation (rTMS) is effective in improving motor function compared to the conventional cerebral rTMS in stroke patients.

Registry

clinicaltrials.gov

Start Date

October 2, 2020

End Date

November 30, 2023

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Samsung Medical Center

Responsible Party

Principal Investigator

Won Hyuk Chang

Associate Professor

Samsung Medical Center

Eligibility Criteria

Inclusion Criteria

•Hemiplegic stroke patients within 1 month after onset
•Moderate to severe motor impairment (Fugl-Meyer assessment \<85)
•Cognitive and language functions to perform more than one step of command
•More than 19 years old

Exclusion Criteria

•Contraindicated to rTMS
•Progressive or unstable stroke
•Pre-existing and active major neurological disease or major psychiatric disease
•A history of advanced liver, kidney, cardiac or pulmonary disease, a terminal medical diagnosis consistent with survival \<1 year

Outcomes

Primary Outcomes

Difference of upper limb motor score in Fugl-Meyer assessment

Time Frame: 2 weeks

(upper limb motor score in Fugl-Meyer assessment at post-intervention) - (upper limb motor score in Fugl-Meyer assessment at baseline) Higher scores mean a better outcome