The Correlation of Cardiopulmonary Exercise Testing and Severity of Pulmonary Artery Hypertension in Patients with Chronic Obstructive Pulmonary Disease
Not Applicable
- Conditions
- Health Condition 1: null- COPD with Pulmonary Artery Hypertension
- Registration Number
- CTRI/2018/02/011657
- Lead Sponsor
- Jamia Milllia Islamia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Severe to very severe COPD patients (as per GOLD criteria) with systolic pulmonary artery hypertension (sPAP) >= 30 mm Hg.
Ability to perform symptom limited cycle ergometer cardiopulmonary test.
Exclusion Criteria
Acute MI (3-5 days) or cardiac disorders
Unstable angina
History of acute viral myocarditis
Syncope
Uncontrolled asthma
Uncontrolled heart failure
Room air desaturation at rest (85%)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method in cardiopulmonary exercise testing <br/ ><br>1.Maximum oxygen uptake(VO2 max) <br/ ><br>2.Oxygen pulse (VO2/ HR) <br/ ><br>3.VD/VT <br/ ><br>4.PETCO2â?¨ <br/ ><br>1.Systolic pulmonary artery pressure (sPAP) <br/ ><br>2.Right atrial pressure (RAP) <br/ ><br>Timepoint: one time
- Secondary Outcome Measures
Name Time Method In Cardiopulmonary exercise testing (CPET) <br/ ><br>1. VO2 @ AT <br/ ><br>2.Peak RER <br/ ><br>3.Peak VE <br/ ><br>4. Heart rate recovery (HRR) <br/ ><br>5. VE/VCO2 <br/ ><br>6.Desaturation (%)Timepoint: one time