CTRI/2018/10/016056
Not Yet Recruiting
N/A
Cardiopulmonary exercise testing as a predictor of postoperative outcome in patients undergoing esophageal cancer surgery following neoadjuvant chemotherapy
ConditionsHealth Condition 1: C00-D49- Neoplasms
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Health Condition 1: C00-D49- Neoplasms
- Sponsor
- AIIMS
- Status
- Not Yet Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Age 18\-75 years
- •2\.ASA I and II
- •3\.All patients of esophagus cancer (squamous cell carcinoma or adenocarcinoma) of the middle or lower third of esophagus, undergoing neoadjuvant chemotherapy followed by transthoracic McEwans or Ivor lewis esophagectomy.
- •4\.Patients giving written informed consent
Exclusion Criteria
- •1\.Contraindications to perform CPET
- •a.Unstable cardiac status (Acute myocardial infarction 3â??5 days, unstable angina, moderate stenotic valvular heart disease, uncontrolled arrhythmias, syncope, active endocarditis, acute myocarditis or pericarditis, hypertrophic cardiomyopathy, uncontrolled heart failure)
- •b.Significant pulmonary hypertension
- •c.Acute pulmonary embolus or pulmonary infarction
- •d.Electrolyte abnormalities
- •e.Thrombosis of lower extremities
- •f.Orthopedic impairment that compromises exercise performance
- •g.Uncontrolled asthma
- •h.Pulmonary oedema
- •i.Room air desaturation at rest \< 85%
Outcomes
Primary Outcomes
Not specified
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