Cardiopulmonary exercise testing as a predictor of postoperative outcome in patients undergoing esophageal cancer surgery following neoadjuvant chemotherapy

AIIMS0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Age 18-75 years
•2.ASA I and II
•3.All patients of esophagus cancer (squamous cell carcinoma or adenocarcinoma) of the middle or lower third of esophagus, undergoing neoadjuvant chemotherapy followed by transthoracic McEwans or Ivor lewis esophagectomy.
•4.Patients giving written informed consent

•1.Contraindications to perform CPET
•a.Unstable cardiac status (Acute myocardial infarction 3â??5 days, unstable angina, moderate stenotic valvular heart disease, uncontrolled arrhythmias, syncope, active endocarditis, acute myocarditis or pericarditis, hypertrophic cardiomyopathy, uncontrolled heart failure)
•b.Significant pulmonary hypertension
•c.Acute pulmonary embolus or pulmonary infarction
•d.Electrolyte abnormalities
•e.Thrombosis of lower extremities
•f.Orthopedic impairment that compromises exercise performance
•g.Uncontrolled asthma
•h.Pulmonary oedema
•i.Room air desaturation at rest < 85%
•j.Respiratory failure
•k.Acute noncardiopulmonary disorder that may affect exercise performance or be aggravated by exercise(i.e. infection, renal failure, thyrotoxicosis)
•l.Mental impairment leading to inability to cooperate
•2.Pregnant patients
•3.Emergency surgery

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