JPRN-UMIN000007638已完成未知
A phase II study of palonosetron combined with dexamethasone to prevent nausea and vomiting induced by daily low-dose cisplatin-based concurrent chemoradiotherapy in patients with uterine cervical cancer. - A phase II study of palonosetron combined with dexamethasone to prevent nausea and vomiting induced by daily low-dose cisplatin-based concurrent chemoradiotherapy in patients with uterine cervical cancer.
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •1) severe, uncontrolled, concurrent illness other than neoplasia; 2) asymptomatic metastases to the brain; 3) seizure disorder needing anticonvulsants unless clinically stable; 4) uncontrolled pleural effusion or ascites; 5) gastric outlet orintestinal obstruction; 6) any vomiting, retching, or grade 2or higher nausea according to CTCAE; 7) a known hypersensitivity to palonosetron, granisetron, or other 5-HT3-receptor antagonists or dexamethasone ingredients; 8) Between registration and administration of the study drug, patients who met the following discontinuation criteria were withdrawn from the study: appeared not to be eligible; received an antiemetic drug within 24 h before administration of study drug; and vomiting, retching, or grade 2 or higher nausea according to CTCAE within 24 h before administration of study drug.
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