Comparison of Prophylactic Intravenous magnesium versus ketamine on Succinylcholine-Induced Fasciculations and Postoperative Myalgia in Patients Undergoing Elective Surgery under General Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- To evaluate the effect of intravenous magnesium sulphate on succinylcholine - induced fasciculations and postoperative myalgia in patients undergoing elective surgery under general anesthesia.
研究概览
简要总结
To compare the effect of intravenous magnesium sulphate and ketamine in succinylcholine - induced fasiculations and postoperative myalgia in patients undergoing elective surgery under general anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status I/II.
- •Patients undergoing elective surgery under general anaesthesia.
排除标准
- •Pregnancy Emergency cases Contraindication to succinylcholine History of neuromuscular disease Patients taking calcium channel blockers, B – blockers Systemic disease – HTN, DM Substance abuse Hyperkalemia Allergic to study drugs.
- •Patients requiring post operative ICU ventilation.
结局指标
主要结局
To evaluate the effect of intravenous magnesium sulphate on succinylcholine - induced fasciculations and postoperative myalgia in patients undergoing elective surgery under general anesthesia.
时间窗: The incidence and severity of succinylcholine induced fasiculations will be observed soon after its administeration and postoperative myalgia will be determined at 0 hour, 6 hour, 12 hour, 24 hour, and 48 hour.
To evaluate the efficacy of intravenous ketamine on succinylcholine - induced fasciculations and postoperative myalgia in patients undergoing elective surgery under general anesthesia.
时间窗: The incidence and severity of succinylcholine induced fasiculations will be observed soon after its administeration and postoperative myalgia will be determined at 0 hour, 6 hour, 12 hour, 24 hour, and 48 hour.
次要结局
- To compare the effect of intravenous magnesium sulphate and ketamine in succinylcholine - induced fasciculations and postoperative myalgia.(To observe the adverse effect associated with the study drugs.)
研究者
Dr Shashi Yadav
Department of Anaesthesia , Shri Ram Murti Smarak Institute of Medical Sciences (SRMS IMS)