Efficacy of exercises to Muscle MRI in patients with neuromuscular diseases and proband
- Conditions
- G12.0G71.0Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]Muscular dystrophy
- Registration Number
- DRKS00005969
- Lead Sponsor
- IVERSITAETSKLINIKUM FREIBURGZentrum für Kinderheilkunde und JugendmedizinKlinik II: Neuropädiatrie und Muskelerkrankungen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 40
patient: children, adolescent and adults with neuromuscular diseases
-testperson: children, adolescent and adults without diseases
Common for both groups:
-age = 5 Jahre
- walk without assistance 10 m
-compliance with training and MRI
-Evidence of signed and dated informed consent/assent document(s) indicating that the
subject (and/or his parent/legal guardian) has been informed of all pertinent aspects of the
trial.
-Contraindication for MRI
-Bad medical condition
-Not able to understand the study and give an assent due to mental retardation
-Non compliance
-Fractures in the past 3 month
--inflammation of the musculoskeletal system
-Venous thrombosis in the past 6 month
-Renal calculus and gallstone
-Acute hernia
-Any lesions at feet
-A surgery in the past 3 month
Special criteria for patients:
-Contractures
-Changed therapy in the last 3 month
Special criteria for testpersons:
-Participation in other trainings for the legs (more than once a week) at the last 6 month
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method awareness about efficacy of the training to the muscle structure of the legs due MRI. Before and after the Training (3 days) is a MRI scheduled.
- Secondary Outcome Measures
Name Time Method evaluation of muscle function due MRI.<br>Before and after the Training (3 days) is a MRI scheduled.