The influence of age dependent changes in muscle components, muscle stiffness and neuro muscular control on the performance during a point-to-point reaction time test

Recruiting

• Conditions: Aging; natuurlijke veranderingen door verouderingsprocessen; muscle performance

• Registration Number: NL-OMON33211
• Lead Sponsor: Vrije Universiteit Brussel (Departement Gerontologie & Geriatrie)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Age between 18 and 31 as well as 70 year and above
Healthy disposition stated by subject
Normal cognition (Mini-Mental-State Examination >26/30),

Exclusion Criteria

Neurological disease,
Inflammatory pathalogy
Musculoskeletal disorders of upper extremities
Metal in body
Pace maker in body
Sport on competitive level

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Component 1 - Primary study parameters: Reactiontime (Descision time and<br /><br>Movement Time), co-contractionratio (sEMG activitivity ratio M Biceps/Triceps<br /><br>Brachii) and movements pattern (acceleratie-deceleratie M. Biceps & Triceps<br /><br>Brachii) during RT-test.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Component 2- primary outcome: Elasticity muscle tendon en musclefibers M.<br /><br>Biceps & Triceps Brachii.<br /><br><br /><br>Component 3- primary outcome: Bandwith of intra-muscular (non fat) collagen<br /><br><br /><br>Component 4 - primary outcome: Level of circulating markers of inflammation<br /><br>(Cytokines, Heat Shock Proteins) and non-enzymatic cross-links (AGEs)<br /><br>determined by ELISA and/or HPLC)</p><br>