Chemotherapy Efficacy and Follow-up Study of Hepatitis B Virus Infection and Reactivation in Children With Leukemia
- Conditions
- Reactivation of Hepatitis B Virus
- Registration Number
- NCT03529760
- Lead Sponsor
- Children's Hospital of Chongqing Medical University
- Brief Summary
Children with clinically diagnosed leukemia may experience occult HBV infection after chemotherapy immunosuppressive therapy, which may affect the normal course of leukemia treatment. However, this is not caused by clinically relevant diagnosis and treatment measures but exists in vivo.
- Detailed Description
The clinical diagnosis of children with leukemia may be due to the influence of leukemia disease on the immune cells of the children and the damage to the immune system due to immunosuppressive therapy in children. Therefore, the risk of contracting hepatitis B virus is relatively high, and some children are In the treatment of immunosuppressive chemotherapy (later), the reactivation of occult HBV infection has an impact on the normal course of leukemia treatment. However, this is not a clinically relevant diagnosis and treatment measure. It is necessary to avoid unnecessary conflicts between clinical doctors and patients as much as possible.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 600
The clinical diagnosis of children with leukemia received systemic chemotherapy.
Children with non-leukemia and children without appropriate treatment.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HBV-DNA positive 1-year Positive HBV nucleic acid test
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chongqing Children's Hospital of Chongqing Medical University
🇨🇳Chongqing, Chongqing, China
Chongqing Children's Hospital of Chongqing Medical University🇨🇳Chongqing, Chongqing, ChinaYao ZhaoContact