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临床试验/NCT04032743
NCT04032743Unknown不适用

Retrospective Study: Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis

Rabin Medical Center1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2018年10月16日最近更新:
适应症

试验速览

阶段
不适用
入组人数
300
试验地点
1
主要终点
survival

研究概览

简要总结

Children treated with intensive chemotherapy are at increased risk for life-threatening infections (sepsis). As the survival of oncology patients increased with the use of aggressive treatment protocols, there was also an increase in the need for hospitalization in intensive care units (ICU) due to sepsis.Several prognostic factors are known to affect the survival of these patients, including the number and type of damaged systems, the type of oncology disease and the duration of neutropenia. With the development of the treatment of ICU, the survival of the oncology patients hospitalized for sepsis has also increased.

We will collect demographic details, details of their oncology and infections, laboratory tests and imaging. The goal is to identify prognostic factors in oncologic children hospitalized in ICU due to sepsis, as well as clinical and laboratory parameters that characterize this group of patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
— 至 19 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Treatment in the hemato-oncology for cancer
  • Admission to the ICU in SCMCI between 2008-2018 because of sepsis during chemotherapy

排除标准

  • Admission to the ICU more than 3 month after last chemotherapy or 1 year after SCT

结局指标

主要结局

survival

时间窗: 30 day

survial status 30 day after release from the ICU

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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