NL-OMON52653招募中不适用
Effect of oral Curcumin on Gut Microbiota Composition in patients with Diabetes Type II, Ulcerative Colitis, Crohn's disease and healthy subjects - Effect of oral curcumin on gut microbiota in various patient populations
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Aged 18-65 years
- •- Stable therapy (i.e. no major dosage changes in the last three months)
- •- Able to give written informed consent
排除标准
- •- Tobacco use (as there are indications this influences the gut microbiota,
- •Huang et al. 2019)
- •- Alcohol use > 1 units/day,
- •- Excessive weight loss of >10% in the last 3 months,
- •- Levels of plasma aspartate aminotransferase (ASAT) and alanine
- •aminotransferase (ALAT) 2.5 times or more the upper limit of the normal range,
- •- Other liver abnormalities,
- •- Known intolerance to curcumin or curcumin-derivatives,
- •- Daily use of non-steroidal anti-inflammatory drugs (NSAIDS),
- •- Use of proton pump inhibitors (as this influences intestinal microbiota
- •composition)
- •- Incomplete information or unwillingness to comply with the intervention,
- •- Participation in other intervention studies 3 months before or after the
- •duration of this study.
研究者
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