Implantation of Bone Marrow Cells to Treat Avascular Necrosis of Femoral Head (ANFH)
Phase 2
- Conditions
- Avascular Necrosis of Femur Head
- Registration Number
- NCT01613612
- Lead Sponsor
- Guangdong Provincial People's Hospital
- Brief Summary
The purpose of this study is to compare the efficacy of autologous enriched bone marrow cell implantation combined with core decompression to single core decompression for the treatment of avascular necrosis of femoral head.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- femoral head necrosis patients
- stage I/II/III (Ficat)
- age from 18 to 55 years
- stop steroid treatment for minimal 6 months
Exclusion Criteria
- age younger than 18 or older than 55
- any hemopathy
- tumor
- femoral head/neck fracture
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method change of Visual Analogue Scale before invention and 24 months after invention Change from baseline in 24 months
change of lequensne algofunctional index before invention and 24 months after invention change from baseline in 24 months
change of WOMAC index before invention and 24 months after invention change from baseline in 24 months
- Secondary Outcome Measures
Name Time Method