Research on the mechanism of cognitive decline in patients after cerebellar pontine angle tumour surgery

• Conditions: cerebellar pontine angle tumour; 10029209; vestibular schwannoma; 10009720

• Registration Number: NL-OMON56566
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- Patients diagnosed with a cerebellar pontine angle tumour (Koos
classification grade 4 schwannoma) that have been operated in the past.
- Control population consisting of patients with unilateral hearing loss due to
a cerebellar pontine angle tumour Koos classification grade 1-4. These control
patients have a *wait and see* policy with annual follow up and did not have
surgery in the past. Control patients will be matched (as far as possible) to
the study population on Koos grade, age, level of education, hearing loss and
tumour side.
- >= 18 years of age
- Dutch proficiency

Exclusion Criteria

- contra-indication for MR imaging
- history of neurofibromatosis type II
- history of cerebellopontine angle surgery or Gamma Knife radiation
- secondary hydrocephalus due to surgery
- concurrent neurological or psychiatric illness
- not able to give informed consent

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified