Effect of Epidural Analgesia on the Parameter ANI During Childbirth
Overview
- Phase
- Not Applicable
- Intervention
- NaCl 0.9%
- Conditions
- Labor Pain
- Sponsor
- Hopital Foch
- Enrollment
- 42
- Locations
- 1
- Primary Endpoint
- Comparison of the ANI parameter with the VAS during labour
- Status
- Terminated
- Last Updated
- 9 years ago
Overview
Brief Summary
There are many methods used for the assessment of pain in the area of anesthesia including heart rate variability which reflects the influence of the autonomic nervous system on the heart. An original index, the ANI (Analgesia Nociception Index), quantifies pain during anesthesia. Obstetric epidural analgesia is particularly suited to evaluate ANI in conscious patients with a comparison of ANI with the measurement of pain by a visual analog scale (VAS).
Evaluation of ANI is performed just before epidural catheter insertion and during the 10 first minutes after saline, sufentanil or lidocaine epidural administration.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Over 18 years,
- •ASA I or II,
- •No history of cardiovascular or respiratory disease
- •No cardiovascular medication
- •No treatment with a tocolytic agent(salbutamol, nicardipine)
- •Desiring epidural analgesia at the early phase of labor pain
Exclusion Criteria
- •Too fast labour
- •A pain score at or above 70 on the pain scale
- •A disturbed EKG signal or extrasystoles
- •Pace-Maker
- •Diabetes mellitus
Arms & Interventions
Group Saline
Epidural administration of saline
Intervention: NaCl 0.9%
Group Sufentanil
Epidural administration of sufentanil
Intervention: Sufentanil
Group Lidocaine
Epidural administration of lidocaine
Intervention: lidocaine
Outcomes
Primary Outcomes
Comparison of the ANI parameter with the VAS during labour
Time Frame: 2 hours
The main objective of the research is to evaluate ANI as a measurment of pain caused by uterine contractions.
Secondary Outcomes
- Effects of epidural sufentanil and of epidural local anesthetic on ANI(2 hours)
- Effects of anxiety score on ANI(2 hours)