Evaluation of the Performance of Epidural Analgesia After Major Abdominal Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Insufficient epidural analgesia
研究概览
简要总结
Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery. However, several studies have reported a failure rate of APT of up to 30%. Its efficacy regarding pain control during coughing and mobilization is also inconsistent, with correct analgesia found in only 60% of cases in a Scandinavian multicenter cohort. Inadequate Epidural analgesia may be associated with more postoperative complications. This finding prompts a study in our institution to evaluate the performance of epidural analgesia after major open abdominal surgery.
详细描述
Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery. However, several studies have reported a failure rate of APT of up to 30%. Its efficacy regarding pain control during coughing and mobilization is also inconsistent, with correct analgesia found in only 60% of cases in a Scandinavian multicenter cohort. Inadequate Epidural analgesia may be associated with more postoperative complications. This finding prompts a study in our institution to evaluate the performance of epidural analgesia after major open abdominal surgery.
Epidural analgesia does not guarantee total control of acute postoperative pain after major open abdominal surgery. The performance of epidural analgesia could vary according to predisposing factors and postoperative days. Inadequate epidural analgesia could be associated with greater morbidity after open major abdominal surgery.
In order to evaluate the performance of epidural analgesia after major open abdominal surgery, a prospective observational monocentric scheme seems relevant. The evaluation will be clinical based on questioning and a brief medical examination during the early postoperative phase of the operated patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major abdominal surgery patient operated by laparotomy (predicted operative time ≥ 2 hours)
- •epidural analgesia accepted
排除标准
- •Minor or protected patient
- •Patients under guardianship, curatorship or safeguard of justice
- •Pregnant or breastfeeding woman
- •Contraindication or refusal of epidural analgesia
- •Failure of the initial placement of the epidural catheter
- •Major intraoperative complication requiring continued postoperative sedation
结局指标
主要结局
Insufficient epidural analgesia
时间窗: day 5
Insufficient epidural analgesia will be defined by the presence of pain assessed by numerical scale \> 3/10 at rest OR on coughing OR on mobilization.
次要结局
未报告次要终点
