Can squeezing blood from the umbilical cord into the baby reduce death and illness in premature babies?
Not Applicable
Completed
- Conditions
- Preterm baby (less than 30 weeks of gestational age)Pregnancy and Childbirth
- Registration Number
- ISRCTN17228884
- Lead Sponsor
- MacKay Children's Hospital
- Brief Summary
2021 Results article in https://doi.org/10.1016/j.jfma.2021.09.013 (added 29/09/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 78
Inclusion Criteria
Preterm (born at less than 30 weeks of gestational age)
Exclusion Criteria
1. Known congenital anomaly
2. Fetal anemia
3. Hydrops fetalis
4. Unknown specific gestational age
5. Umbilical cord is less than 20 cm long
6. Received resuscitation after birth and receiving one or more doses of epinephrine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Neonate's hemoglobin level at admission<br> 2. Neonate's hematocrit at admission<br> 3. Neonate's mean arterial pressure at admission<br> 4. Administration of inotropic agents in first 72 h post-birth<br> All data will be taken from medical records.<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Rate of death before post-menstrual age (PMA) of 36 weeks assessed by reviewing the patient’s medical records<br> 2. Rate of bronchopulmonary dysplasia assessed by reviewing the patient’s medical records<br> 3. Rate of all-stage intraventricular hemorrhage assessed by reviewing the patient’s medical records<br> 4. Rate of severe intraventricular hemorrhage assessed by reviewing the patient’s medical records<br> 5. Rate of necrotizing enterocolitis assessed by reviewing the patient’s medical records<br> 6. Rate of retinopathy of prematurity assessed by reviewing the patient’s medical records<br> Neonates will be followed up from birth until first discharge from hospital.<br>