Evaluation of bone repair using a blood concentrate

Not Applicable

• Conditions: Inflammation; pain; edema; cervical atlas; C23.888.592.612; C23.888.277; C23.550.470; A02.835.232.834.151.500

• Registration Number: RBR-64vgjd
• Lead Sponsor: niversidade de Pernambuco

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

The established inclusion criteria are: age between 18 and 35 years old; no systemic disease; not to use medications that interfere with the procedure on the day or week prior to the research; present surgical site without current signs and symptoms of infection; agree to participate in the experiment; present lower third molars in similar positions.

Exclusion Criteria

Patients with: (1) history of pregnancy or lactation, (2) history of allergy to any drug used in the experiment; (3) not participate in all phases of the proposed research; (4) and not having the lower second molars.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to evaluate, with this study, to evaluate if L-PRF has a positive influence on the aveolar repair process after lower third molar extractions, increasing bone neoformation, which was evaluated by computed tomography.

Secondary Outcome Measures

Name	Time	Method
It is hoped with this study, to evaluate whether L-PRF is more effective in controlling pain and edema compared to negative control after lower third molar extraction. Verified by visual analog scale within 7 days (pain), 5 preoperative and 72h postoperative facial measurements (edema)