Efficacy of Bone Repair in Periapical Dental Lesions Using Different Methods: Platelet Aggregates with Autologous Platelet Rich Fibrin Membranes (L-PRF) Versus Bone Repair with Clot
Not Applicable
Terminated
- Conditions
- Radicular CystD014947
- Registration Number
- RBR-7wc8dnw
- Lead Sponsor
- Pontifícia Universidade Católica do Paraná
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Presence of an apical lesion in an anterior maxillary tooth, well filled in the region surrounding the intracanal pin and with a prosthetic crown without infiltration and without any indication for removal, so that there is no risk of tooth fracture when the pin is removed; Patients that return with the active infectious process after root canal retreatment and that it is adequately shaped and filled.
Exclusion Criteria
As exclusion criteria: patients with systemic diseases such as diabetes mellitus blood dyscrasias, with thrombocytopenia below, 150,000 mm3
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The results of this study showed a statistically significant difference in bone pocket repair when the L-PRF (Leukocyte Platelet Rich Fibrin) membrane was used in relation to the blood clot. There was a significant difference regarding the decrease in bone store volume after 90 days, both for the L-PRF(Leukocyte Platelet Rich Fibrin) membrane and for the blood clot. The group that used L-PRF (Leukocyte Platelet Rich Fibrin) was more effective in terms of bone repair, decreasing the size of the bone store in volume, than the group that used the blood clot, after 90 days, the decrease was 48.48% for the L-PRF(Leukocyte Platelet Rich Fibrin) and 29.26% for blood clot, and this percentage was also statistically significant.
- Secondary Outcome Measures
Name Time Method Secondary outcomes are not expected.