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临床试验/CTRI/2025/10/096412
CTRI/2025/10/096412尚未招募不适用

Association of propofol induction dose and post induction hypotension with varying doses of propofol in elderly in non cardiac surgery a randomised control trial

Manipal Hospitals1 个研究点 分布在 1 个国家目标入组 168 人开始时间: 2025年11月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
168
试验地点
1
主要终点
To evaluate the hemodynamic changes post induction in both doses of propofol by studying the vital signs in 2 groups for 11 mins post induction

研究概览

简要总结

A randomized controlmstudy to asses the incidence of post induction hypotension in patientundergoing general anatgesia with ET tube placement with 2 doses of propofol and to asses the viral(HR,SBP,DBP, MAP) will bd assejsd from 3 minutes before induction to 10 minitues after intubation along with airway assesment and duration of laryngoscopy. The need for pressor treatment will be documented

The intubation quality score,alderete score and Ramsay sedation score will be asseseed at intubation and discharge from PACU respectively

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
65.00 Year(s) 至 85.00 Year(s)(—)
性别
All

入选标准

  • ASA I/II/III PATIENT AGE MORE THAN OR EQUAL TO 65 YEARS OF ANY GENDER PATIENTS UNDERGOING GA WITH ET TUBE PLACEMENT.

排除标准

  • Patient refusal to participate in the study.
  • Patient allergic to propofol.
  • ASA IV grading of patients.
  • Patients undergoing surgeries which do not need general anaesthesia or placement of endotracheal tube.

结局指标

主要结局

To evaluate the hemodynamic changes post induction in both doses of propofol by studying the vital signs in 2 groups for 11 mins post induction

时间窗: To evaluate the hemodynamic changes post induction in both doses of propofol by studying the vital signs in 2 groups for 11 mins post induction

次要结局

  • 1 to asses induction quality score for 2 dses of propofol(2. to asses Ramsy Sedation scale at extubation)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

DR HS MURTHY

Manipal Hospital,Old Airport Road

研究点 (1)

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