Comparison of Efficacy & Tolerability Of Polyethylene Glycol 4000 Versus Polyethylene Glycol 3350+ Electrolytes For Fecal Disimpaction in Pediatric Functional Constipation: A Double-Blind Randomized Controlled Trial - NI

Institute of Medical sciences (IMS) and SUM Hospitalk0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月1日

试验速览

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•1-16 years age admitted to the inpatient department
•2. Having h/o functional constipation as per ROME IV criteria
•3)with Fecal impaction defined as
•A hard mass in the lower abdomen identified on physical examination or
•Dilated rectum filled with large amount of stool on per rectal Examination or
•Excessive stool in the colon on abdominal radiography as determined by a radiologist

•1) Patients with drug-induced constipation
•2) Organic constipation ie,
•I.Neurological disorders eg. Neural tube defects/cerebral/motor neuron diseases/neuro regression syndromes
•II.Hirschsprung disease, or anal anomalies
•III.Known metabolic or endocrine disorders
•3) Patients with previous gastrointestinal surgery (except appendectomy)
•4) Children with suspected gastrointestinal obstruction
•5) Patients taking PEG (either at the time of enrolment or within 2 month before enrolment)
•6) Patients receiving medication at enrolment or within 1 month before enrolment influencing gastrointestinal motility function (eg, lactulose, loperamide, cisapride)
•7) Known history of Allergy to PEG formulations
•8) Patients having comorbidity of any other system like CVS/Respiratory/CNS etc
•9)Known case of Chronic kidney disease or history of acute kidney injury in past 3 monthes

发起方

Institute of Medical sciences (IMS) and SUM Hospitalk